Ronald Kong Selected Research

emvododstat

2/2022	In vitro metabolism, pharmacokinetics and drug interaction potentials of emvododstat, a DHODH inhibitor.
1/2022	Emvododstat, a Potent Dihydroorotate Dehydrogenase Inhibitor, Is Effective in Preclinical Models of Acute Myeloid Leukemia.
1/2021	The DHODH inhibitor PTC299 arrests SARS-CoV-2 replication and suppresses induction of inflammatory cytokines.
8/2020	The DHODH Inhibitor PTC299 Arrests SARS-CoV-2 Replication and Suppresses Induction of Inflammatory Cytokines.
1/2019	Targeting of Hematologic Malignancies with PTC299, A Novel Potent Inhibitor of Dihydroorotate Dehydrogenase with Favorable Pharmaceutical Properties.

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Ronald Kong Research Topics

Disease

4	Neoplasms (Cancer) 01/2022 - 01/2019
3	COVID-19 02/2022 - 08/2020
3	Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker) 01/2021 - 01/2020
2	Leukemia 01/2022 - 01/2019
2	Inflammation (Inflammations) 01/2021 - 08/2020
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2022
1	Glioblastoma (Glioblastoma Multiforme) 10/2021
1	Diffuse Intrinsic Pontine Glioma 10/2021
1	Leiomyosarcoma 10/2021
1	Body Weight (Weight, Body) 01/2021
1	Hematologic Neoplasms (Hematological Malignancy) 01/2019

Drug/Important Bio-Agent (IBA)

5	emvododstatIBA 02/2022 - 01/2019
5	Pharmaceutical PreparationsIBA 10/2021 - 01/2019
3	Dihydroorotate DehydrogenaseIBA 02/2022 - 01/2019
2	pyrimidineIBA 01/2022 - 01/2019
2	NucleotidesIBA 01/2022 - 01/2019
2	TubulinIBA 10/2021 - 01/2021
2	PTC596IBA 10/2021 - 01/2021
2	CytokinesIBA 01/2021 - 08/2020
1	Temozolomide (Temodar)FDA LinkGeneric 10/2021
1	Dacarbazine (DIC)FDA LinkGeneric 10/2021
1	deflazacortIBA 12/2020
1	atalurenIBA 01/2020
1	Nonsense Codon (Nonsense Mutation)IBA 01/2020
1	Carboxylic AcidsIBA 01/2020
1	EnzymesIBA 01/2019
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2019
1	Phosphotransferases (Kinase)IBA 01/2019
1	Uracil NucleotidesIBA 01/2019
1	Biological ProductsIBA 01/2019

Therapy/Procedure

2	Therapeutics 01/2021 - 08/2020